Efeito dos probióticos nas dislipidemias: a scoping review

Abstract

Dyslipidemia is a major risk factor for chronic noncommunicable diseases and has been associated with changes in the composition of the intestinal microbiota and intestinal barrier, leading to a number of health disorders, such as intestinal dysbiosis. The consumption of probiotics has been pointed out as a therapeutic alternative for the treatment of dyslipidemia. Objective: To review the literature on the effect of probiotics in the treatment of dyslipidemia. Methodology: This is a literature review of the scoping review type, with a search in the databases Medline (PubMed), SciELO, VHL and LILACS. The probiotic DECS, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and intestinal microbiota, and their respective correlates were used for the English language. We included articles in humans, of both sexes, aged over 18 years and presenting the values of lipid fractions before and after treatment with probiotics. Results: We included 16 studies between the periods 2009 to 2018, where 81,25% (n = 13) had positive effects, from 3 weeks, with total cholesterol and low density lipoprotein being the most action sensitive parameters of probiotics. Conclusion: Probiotics may be an important adjunct in the treatment of dyslipidemia, however, due to the great heterogeneity of studies, considering the new thematic, it is important to continue the studies on the subject in humans.