Browsing by Author "Santos, Isabel Reis Oliveira dos"
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Item Efeito do uso de probióticos sobre os sintomas da depressão: revisão sistemática(Universidade Católica do Salvador, 2021-12-13) Santos, Dhafine Palhano Tavares; Menezes, Gisele Barreto Lopes; http://lattes.cnpq.br; Santos, Isabel Reis Oliveira dos; http://lattes.cnpq.br; Brandão, Najara Amaral; http://lattes.cnpq.brIntroduction: Considered the “evil of the century”, depression is a contemporary phenomenon, due to the high epidemiological indices. Scientific studies demonstrate that the use of probiotics can be beneficial in reducing depressive symptoms, as they can act on stimuli in the brain centers that initiate behavioral responses. Objective: Systematically review, randomized clinical studies involving probiotic supplementation and its effects on depressive symptoms. Methodology: A systematic search in the SciELO, BVS, Pubmed and LILACS databases was performed, resulting in the selection of 10 double and triple-blind clinical studies, randomized and placebo-controlled on the use of probiotics as an adjuvant treatment for depression. Data were presented in a table, containing information such as probiotic strains, treatment duration and psychological outcome. Results: Eight articles showed a significant beneficial effect regarding the reduction of depressive symptoms or depression scales, with Lactobacillus and Bifidobacterium being the most used probiotic strains. Conclusion: The use of probiotics to alleviate depressive symptoms shows promising results, but larger and more rigorous randomized, double-blind, placebo-controlled clinical trials are still needed to assess these conclusions.Item Efeito dos probióticos nas dislipidemias: a scoping review(Universidade Católica do Salvador, 2019-06-07) Santos, Isabel Reis Oliveira dos; Ferreira, Andréa Jaqueline Fortes; lattes.cnpq.br; Menezes, Gisele Barreto Lopes; lattes.cnpq.br; Meneses, Gisele Barreto Lopes; lattes.cnpq.br; Cerqueira, Lara Gabriela Araújo; lattes.cnpq.br; Barreto, Iasmim Santos; lattes.cnpq.brDyslipidemia is a major risk factor for chronic noncommunicable diseases and has been associated with changes in the composition of the intestinal microbiota and intestinal barrier, leading to a number of health disorders, such as intestinal dysbiosis. The consumption of probiotics has been pointed out as a therapeutic alternative for the treatment of dyslipidemia. Objective: To review the literature on the effect of probiotics in the treatment of dyslipidemia. Methodology: This is a literature review of the scoping review type, with a search in the databases Medline (PubMed), SciELO, VHL and LILACS. The probiotic DECS, dyslipidemia, hypercholesterolemia, hypertriglyceridemia and intestinal microbiota, and their respective correlates were used for the English language. We included articles in humans, of both sexes, aged over 18 years and presenting the values of lipid fractions before and after treatment with probiotics. Results: We included 16 studies between the periods 2009 to 2018, where 81,25% (n = 13) had positive effects, from 3 weeks, with total cholesterol and low density lipoprotein being the most action sensitive parameters of probiotics. Conclusion: Probiotics may be an important adjunct in the treatment of dyslipidemia, however, due to the great heterogeneity of studies, considering the new thematic, it is important to continue the studies on the subject in humans.